Classes of beta blockers and their mechanisms of actions

Here is a example of a essay of the subject I’m looking for. Beta blockers are used for several medical conditions such as hypertension, congested heart failure, abnormal heart rhythms, and many off- label uses. Beta blockers work by blocking the hormone called epinephrine from binding to the receptors. They affect the cardiac oxygen supply-demand by decreasing the force of myocardial contractility and heart rate. There are two types of Beta Blockers; selective and non-selective. Selective beta blocker block Beta1(heart). Non- selective beta blocker blocks Beta1(in the heart) and Beta2 (in the lungs). Woo & Robinson (2015), discussion on beta blockers addresses selective beta blocker such as Metoprolol and Atenolol work on the heart and will cause reduced cardiac output, therefore reducing blood pressure. Non-selective beta blockers such as Coreg and Propranolol block beta1 and beta2; working on the heart and the lungs, can also affect the kidney, eyes and other body systems. Coreg (non-selective) is contraindicated in asthma patients. Patient with renal impairments must have dose of beta blocker reduced by 50-75% depending on renal function. Beta blockers should not be given with calcium channel blockers due to adverse cardiac effects. Woo & Robinson (2015), addressed beta blockers such as Propranolol (non-selective) can be used off label for migraine headaches. Beta blockers should be used with caution in diabetics due to their ability to mask hypoglycemia with diaphoresis being the only indicator. Using Beta blocker with OTC cold medications may result in hypertension or tachycardia. Selective Beta blockers are more appropriate for use in patients with COPD, PVD, diabetes and asthma. Beta blockers are contraindicated in the first trimester of pregnancy

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